Pizensy (lactitol) is an osmotic laxative indicated for the treatment of chronic idiopathic constipation (CIC) in adults.

Pizensy (lactitol) is an osmotic laxative indicated for the treatment of chronic idiopathic constipation (CIC) in adults.

-INDICATIONS AND USAGE

 PIZENSY is an osmotic laxative indicated for the treatment of chronic idiopathic constipation (CIC) in adults.

DOSAGE AND ADMINISTRATION 

The recommended adult dosage of PIZENSY is 20 grams orally once daily, preferably with meals [see Clinical Pharmacology . 
Reduce the dosage to 10 grams once daily for persistent loose stools. 
 Administer oral medications at least 2 hours before or 2 hours after PIZENSY

 Preparation and Administration Instructions 

PIZENSY Multi-dose bottle NOTE: 

The bottle top is a measuring cap marked to contain 10 grams of powder when filled to the top of white section in the cap marked by the arrow. 

1.Using the measuring cap, measure the prescribed dose. • 20-gram dose: Fill the measuring cap twice to the top of the white section in cap marked by the arrow. • 10-gram dose: Fill the measuring cap once to the top of the white section in cap marked by the arrow. 

2. Pour the measured dose into an empty 8-ounce glass. 

3. Add 4 ounces to 8 ounces of water, juice or other common beverages (coffee, tea, soda) and stir to dissolve. 

4. Drink the entire contents of the glass.

 PIZENSY Unit-dose packets 

1. Pour the contents of one or two unit-dose packets, as prescribed, into an empty 8-ounce glass. 

2. Add 4 ounces to 8 ounces of water, juice or other common beverages (coffee, tea, soda) to the glass containing the powder and stir thoroughly to dissolve.

 3. Drink the entire contents of the glass

DOSAGE FORMS AND STRENGTHS 

PIZENSY is a white to off-white crystalline powder for oral solution supplied as:

280 grams of lactitol in multi-dose bottles 

 560 grams of lactitol in multi-dose bottles 

 10 grams of lactitol in unit-dose packets  

PIZENSY is contraindicated in patients with:

 • known or suspected mechanical gastrointestinal obstruction 

• galactosemia  

Adverse reactions 

Common adverse reactions (≥ 3%) include upper respiratory tract infection, flatulence, diarrhea, increased blood creatinine phosphokinase, abdominal distension, and increased blood pressure

Referance-

1.https://www.drugs.com/history/pizensy.html

2.https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/211281s000lbl.pdf